PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 24, 2026SLEEP0 citations

Facility-Measured Sleep Electroencephalographic Microstructures in Long COVID

View Full Paper
HSHaoqi SunRDRammy DangPLP H M LiBroad Institute

Key Points

  • To investigate the relationship between long COVID, ME/CFS, and changes in sleep EEG microstructures.
  • Analyzed sleep EEG data in individuals with long COVID and ME/CFS
  • Compared EEG findings to identify pathological microstructure changes
  • Participated in two clinical trials related to sleep and inflammation
  • Identified significant alterations in sleep EEG microstructures in long COVID and ME/CFS
  • Findings suggest a relationship between these changes and post-infectious brain activity
  • Highlights potential impacts on clinical approaches for managing long COVID and ME/CFS

Abstract

These findings suggest that LC and ME/CFS are associated with plausibly pathological sleep EEG microstructure changes, illuminating the pathobiology of post-infectious processes on brain activity.CLINICAL TRIAL INFORMATIONTrial 1: Sleep and Inflammatory Resolution Pathway, https://clinicaltrials.gov/study/NCT03377543, NCT03377543.Trial 2: Pain in Long COVID-19: the Role of Sleep, https://clinicaltrials.gov/study/NCT05606211, NCT05606211.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Sun et al. (2026) studied this question.

synapsesocial.com/papers/69eb099a553a5433e34b3fc3https://doi.org/10.1093/sleep/zsag090
Ask AI
Helpful
Bookmark
Share
View Full Paper

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1ppcor: An R Package for a Fast Calculation to Semi-partial Correlation Coefficients2015 · 1,191 citations
  2. 2Effects of Bedtime Very Low Dose Cyclobenzaprine on Symptoms and Sleep Physiology in Patients with Fibromyalgia Syndrome: A Double-blind Randomized Placebo-controlled Study2011 · 92 citations
  3. 3Sleep and synaptic homeostasis: a hypothesis2003 · 1,217 citations
  4. 4Defining the Occurrence and Influence of Alpha-Delta Sleep in Chronic Fatigue Syndrome2007 · 39 citations
  5. 5Decreased Sleep Spindles and Spindle Activity in Midlife Women with Fibromyalgia and Pain2004 · 109 citations