Preoperative computed tomography for assessment of bone invasion in oral squamous cell carcinoma: diagnostic accuracy and anatomical subsite dependency

Jannik Ketschau; Yannik Leonhardt; Alex Grabenhorst; H. Singer; Helena Kram; Nils Krautkremer; Cornelius Leopold; Jonathan Mohr; Herbert Stimmer; Klaus-Dietrich Wolff; Lucas M. Ritschl

doi:10.1007/s00432-026-06472-2

April 22, 2026Journal of Cancer Research and Clinical OncologyOpen Access

Preoperative computed tomography for assessment of bone invasion in oral squamous cell carcinoma: diagnostic accuracy and anatomical subsite dependency

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Key Points

The study aims to evaluate the diagnostic accuracy of preoperative CT in assessing bone invasion in oral squamous cell carcinoma across different anatomical subsites.
Analyzed the performance of preoperative CT scans in relation to bone invasion detection.
Assessed variations in diagnostic accuracy based on anatomical location, radiological severity, and image quality.
CT demonstrated varied diagnostic performance in identifying bone invasion depending on the anatomical subsite.
The quality of the images and the severity of the disease significantly influenced diagnostic outcomes.
A localization-aware approach may improve treatment decisions by reducing the risks of undertreatment or overtreatment.

Implication

Preoperative CT identifies bone invasion in oral squamous cell carcinoma, suggesting variability across anatomical subsites.

Abstract

Preoperative CT provides clinically relevant information for assessing bone invasion in OSCC. However, diagnostic performance varies across anatomical subsites, as well as radiological severity and image quality. A localization-aware interpretation may help to avoid under- and overtreatment.

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Cite This Study

Ketschau et al. (2026) studied this question.

synapsesocial.com/papers/69eb0ac4553a5433e34b4c45 https://doi.org/10.1007/s00432-026-06472-2

View Full Paper

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Preoperative computed tomography for assessment of bone invasion in oral squamous cell carcinoma: diagnostic accuracy and anatomical subsite dependency

Key Points

Implication

Abstract

Discussion

Cite This Study

Preoperative computed tomography for assessment of bone invasion in oral squamous cell carcinoma: diagnostic accuracy and anatomical subsite dependency

Key Points

Implication

Abstract

Discussion

Cite This Study

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