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April 24, 2026The Journal of Clinical Endocrinology & MetabolismOpen Access

The Acromegaly Patient Experience: Burden of Treatment, Breakthrough Symptoms, and Quality of Life

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Authors

EGEliza B. GeerJSJill Sisco

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Overview

Review highlights treatment burden and symptom persistence in acromegaly, indicating impaired quality of life.

Key Points

  • The aim is to synthesize the burden of treatment and persistent symptoms affecting the quality of life in acromegaly.
  • Reviewed data from clinical trials, longitudinal cohorts, and registry studies.
  • Evaluated patient-reported outcomes related to symptoms, mood, and functioning.
  • Examined the impact of various therapies on patient experiences.
  • Many patients continue to experience symptoms despite biochemical control.
  • Health-related quality of life remains significantly impaired, especially in psychological and social areas.
  • Increased treatment burden and ongoing symptoms negatively affect productivity and overall well-being.

Cite This Study

Geer et al. (2026) studied this question.

synapsesocial.com/papers/69eb0ac4553a5433e34b4c8chttps://doi.org/10.1210/clinem/dgag122
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