Umpolung Reactivity of N-Sulfonylhydrazones and Imino Esters to Access Functionalized Oxazoles

Key Points

• The aim is to synthesize functionalized oxazoles using umpolung reactivity of N-sulfonylhydrazones and imino esters.
• Synthesis of functionalized oxazoles via N-sulfonylhydrazones and imino esters
• Light-induced N–S bond cleavage to produce intermediates
• Formation of nucleophilic diazo compounds
• Successful synthesis of various functionalized oxazoles
• Demonstrated effective umpolung reactivity
• Intermediates displayed nucleophilic properties leading to further functionalization