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January 1, 2026Dalton TransactionsOpen Access

Investigation of the metal-binding site 2 of Y. pestis YfeA protein: solution studies of Fe( ii ), Mn( ii ), and Zn( ii ) complexes

Bartosz Orzeł Małgorzata Ostrowska Sławomir Potocki Massimiliano Peana Elzbieta Gumienna-Kontecka

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Key Points

The central aim is to investigate the metal-binding site 2 of the YfeA protein in Yersinia pestis.
Characterization of metal-binding capabilities of YfeA Site 2 peptide model.
Comparative analysis of Fe(II), Mn(II), and Zn(II) complexes.
Detailed identification of metal-binding sites.
Comparison shows distinct binding affinities for each metal.

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Implication

This investigation characterizes metal-binding capabilities in a peptide model, implicating protein functionality.

Abstract

This work presents a detailed characterization and comparative analysis of the metal-binding capabilities of YfeA Site 2 peptide model.

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Cite This Study

Orzeł et al. (2026) studied this question.

synapsesocial.com/papers/69eb0b50553a5433e34b521f https://doi.org/10.1039/d6dt00422a

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