Shows concordance of claudin 18.2 expression in cytology and surgical specimens, suggesting improved testing access for therapies.
Cytology specimens could serve as a reliable source for CLDN18.2 biomarker testing when interpreted at the threshold of 75% or above. Although discrepancies occur in some cases, the findings support the incorporation of cytology into biomarker testing workflows to expand access to CLDN18.2-targeted therapies for patients lacking surgical specimens.
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Yang et al. (2026) studied this question.
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