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April 25, 2026BMC Pulmonary Medicine0 citationsOpen Access

Bronchopleural fistula after lobectomy: retrospective study of different treatment solutions

SLShihu LiuHZHefeng ZhangYDYanfeng Dong

Key Points

  • To evaluate different treatment strategies for bronchopleural fistula (BPF) following lobectomy and their outcomes.
  • Retrospective review of 7,550 lobectomy patients from 2016 to 2023
  • Analysis of treatment approaches, clinical outcomes, and factors influencing management
  • Comparison of mortality rates between conservative management and active interventions
  • Of the 43 patients with BPF, conservative management had a 90-day mortality of 29.2%
  • Active interventions led to a significantly lower mortality rate of 10.2%
  • Intraoperative reinforcement of the bronchial stump with fat tissue may improve outcomes for patients with risk factors.

Abstract

Bronchopleural fistula is an abnormal communication between the bronchial tree and the pleural cavity. Management strategies may vary significantly among physicians within the same institution, largely due to differences in clinical judgement and the absence of standardised treatment guidelines. We retrospectively reviewed the medical records of patients diagnosed with BPF at the Affiliated Hospital of Qingdao University between 2016 and 2023. Data on etiology, nutritional status, surgical site, treatment approach, drainage duration, and patient outcomes were analyzed. During the study period, 7,550 patients underwent lobectomy, of whom 43 (0.57%) developed postoperative BPF. Among the 24 patients managed conservatively, the 90-day mortality rate was 29.2%. In contrast, the 19 patients who received active interventions had a significantly lower 90-day mortality of 10.2%. Selection of an appropriate treatment strategy is critical in the management of BPF. In patients with identifiable risk factors, intraoperative reinforcement of the bronchial stump with fat tissue may be considered. Overall, management strategies should be individualized according to patient characteristics, fistula features, and the clinical context.

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Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/69ec59fc88ba6daa22dab942https://doi.org/10.1186/s12890-026-04218-x
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