Establishes a BALB/c mouse model for studying UV-induced dermatological changes, suggesting practical applications for human skin research.
The BALB/c mouse model effectively mimics human photoaging under chronic UV exposure using a two-MED protocol, which corresponds to a total dose of 51.8 J/cm² UVA and 5.53 J/cm² UVB. This practical model, which exhibits skin features comparable to those of humans, provides a closer approximation of human skin responses for comprehensive studies on the mechanisms and interventions of photoaging.
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Huynh et al. (2026) studied this question.
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