A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin

Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

1. 1A System for Stable Expression of Short Interfering RNAs in Mammalian Cells2002 · 4,314 citations
2. 2Mutation in a heterochromatin-specific chromosomal protein is associated with suppression of position-effect variegation in Drosophila melanogaster.1990 · 598 citations
3. 3Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes2002 · 240 citations
4. 4Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation2002 · 561 citations