Key result
Women with ischemic heart disease experience persistently higher adjusted morbidity and mortality compared with men, presenting with more angina but less obstructive coronary artery disease.
Why the study?
Sex-related differences persist in the epidemiology, presentation, diagnostic testing, and management of ischemic heart disease, with persistently higher adjusted morbidity and mortality in women.
Answers are grounded in this paper and cite their sources.
This review highlights significant sex-related differences in ischemic heart disease, noting that women experience more angina but less obstructive CAD, leading to diagnostic delays and higher morbidity.
There are sex-related differences in the epidemiology, presentation, diagnostic testing, and management of Ischemic heart disease (IHD) in women compared with men. The adjusted morbidity and mortality are persistently higher, particularly in younger women and blacks. Women have more angina but less obstructive CAD which affects delays in presentation and diagnosis and testing accuracy. The non-biological factors play a significant role in access to care, IHD management, and guideline adherence. Future research focus includes sex-specific outcomes, characterization of the biologic differences and implementation science around quality of clinical care.
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Nussbaum et al. (2022) conducted a review in Ischemic heart disease. Women with ischemic heart disease experience persistently higher adjusted morbidity and mortality compared with men, presenting with more angina but less obstructive coronary artery disease.
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