The aim of this study was to investigate the efficacy of concentrated growth factor (CGF) in type 1 tympanoplasty. This study represents a retrospective analysis of a non-randomized interventional cohort study, included 60 patients who underwent primary type 1 tympanoplasty between November 2024 and July 2025. The patients were divided into those who received only a cartilage graft (n = 30) and those who received a cartilage graft and CGF (n = 30). The incidence rates of residual tympanic membrane perforation, audiological outcomes, and postoperative infection rates were compared. The incidence rate of residual perforation was significantly lower in the CGF group than in the cartilage-only group. The audiological outcomes showed no significant differences between the groups. Postoperative infection was observed less frequently in the CGF group. CGF may represent a promising adjunct in type 1 tympanoplasty by potentially supporting graft integration and reducing residual perforation rates.
Tutar et al. (2026) studied this question.