Why the study?
Inflammatory bowel disease involves inflammation and altered hemostatic and immune responses that may increase thrombotic and infectious risks, which could influence TAVR outcomes.
Does the presence of inflammatory bowel disease increase the risk of adverse outcomes in adults undergoing transcatheter aortic valve replacement?
Cohort (n=103,372)
Yes
Does the presence of inflammatory bowel disease increase the risk of adverse outcomes in adults undergoing transcatheter aortic valve replacement?
Effect estimate: RR 1.45 (95% CI 1.34-1.56)
p-value: p=<0.0001
Inflammatory bowel disease is associated with significantly increased 1-year mortality and peri-procedural complications following TAVR, highlighting the need for tailored peri-procedural management in this vulnerable population.
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Afridi et al. (2026) conducted a cohort in Transcatheter Aortic Valve Replacement (TAVR) (n=103,372). Inflammatory Bowel Disease (IBD) vs. No Inflammatory Bowel Disease was evaluated on All-cause mortality (RR 1.45, 95% CI 1.34-1.56, p=<0.0001).
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