Updated glucose management indicator (GMI) better aligns with HbA1c than current GMI: implications for clinical practice and reporting | Synapse
April 26, 2026Open Access
Updated glucose management indicator (GMI) better aligns with HbA1c than current GMI: implications for clinical practice and reporting
Key Points
This research aims to evaluate the accuracy of the updated glucose management indicator (uGMI) compared to the CGM-derived GMI in relation to HbA1c levels.
Evaluated the consistency of uGMI and CGM-derived GMI against HbA1c levels.
Analyzed performance at both low and high HbA1c ranges (<42mmol/mol and >58mmol/mol).
uGMI showed improved accuracy in aligning with HbA1c, particularly at lower levels (<42mmol/mol).
At higher HbA1c levels (>58 mmol/mol), uGMI also demonstrated better agreement than the CGM-derived GMI.
Abstract
Compared with the CGM-derived GMI, the uGMI provides more accurate and consistent agreement with HbA1c, particularly at lower (58 mmol/mol or 7.5% NGSP) HbA1c levels.