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April 26, 2026Korean Journal of GastroenterologyOpen Access

Immunotherapy and Targeted Therapy for Advanced Biliary Tract Cancer

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Authors

ILIn Ho LeeSYSeung Bae Yoon

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Overview

Review highlights therapeutic advancements in biliary tract cancer, focusing on immunotherapy and targeted therapies, suggesting improved outcomes.

Key Points

  • The central aim is to review recent advances in immunotherapy and targeted therapy for biliary tract cancer (BTC).
  • Overview of clinical trials focusing on immunotherapy and targeted therapy for BTC.
  • Integration of molecular profiling with treatment strategies.
  • Analysis of therapeutic efficacy and limitations.
  • Immunotherapy showed meaningful activity in advanced BTC, especially when combined with chemotherapy.
  • Identified actionable genomic alterations, such as FGFR2 fusions and IDH1 mutations, for targeted therapies.
  • Need for predictive biomarkers to optimize patient selection remains a critical issue.

Cite This Study

Lee et al. (2026) studied this question.

synapsesocial.com/papers/69edac2e4a46254e215b3f37https://doi.org/10.4166/kjg.2026.021
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