PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
April 26, 2026Diabetes Obesity and Metabolism4 citations

Comparative Effects of Different Exercise Modalities on Circulating Adipokines and Inflammatory Cytokines in Adults With Type 2 Diabetes: A Network Meta‐Analysis

View Full Paper
HYHenghao YanMZMinjia ZhuangQLQian Liu

Key Points

  • This analysis aims to compare the effects of different exercise modalities on circulating adipokines and inflammatory cytokines in adults with type 2 diabetes.
  • Conducted a network meta-analysis comparing aerobic exercise and resistance training effects.
  • Evaluated associations with outcomes related to adipokines and inflammation in adults with type 2 diabetes.
  • Exploratory analyses assessed variances across age and weight subgroups, as well as training frequency and session duration.
  • Aerobic exercise consistently showed favorable changes in adipokine-related outcomes.
  • Resistance training was associated with larger effects on certain inflammation-related outcomes.
  • IL-6 findings are inconsistent and require cautious interpretation.

Abstract

AE and RT demonstrated different association patterns with adipokine- and inflammation-related outcomes in adults with T2DM. AE was more consistently associated with favourable adipokine-related changes, whereas RT showed comparatively larger associations with some inflammation-related outcomes. Additional exploratory analyses suggested that these patterns may vary across age and weight subgroups, and that training frequency and session duration may also be associated with selected outcomes. However, the IL-6 findings should be interpreted with particular caution because the corresponding network showed local inconsistency. Therefore, these results should be regarded as hypothesis-generating rather than as a basis for modality prioritization or formal exercise recommendations.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Yan et al. (2026) studied this question.

synapsesocial.com/papers/69edacbd4a46254e215b47dchttps://doi.org/10.1111/dom.70780
Ask AI
Helpful
Bookmark
Share
View Full Paper