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April 26, 2026Journal of Clinical Gastroenterology0 citations

Utility of Oesophagogastroduodenoscopy in Lynch Syndrome

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DTDouglas TjandraOSOmar SalehiJKJadon Karp

Key Points

  • The aim is to evaluate the effectiveness of oesophagogastroduodenoscopy in identifying lesions in patients with Lynch syndrome.
  • Evaluated a cohort of patients with Lynch syndrome for the presence of lesions via OGD.
  • Assessed the rates of premalignant, dysplastic, and malignant lesions detected during the procedures.
  • Found a 22.6% prevalence of premalignant, dysplastic, or malignant lesions.
  • High-risk lesions were more frequently located in the duodenum.

Abstract

Our Lynch syndrome cohort demonstrated high rates of premalignant, dysplastic or malignant lesions (22.6%). High-risk lesions showed a predilection for the duodenum. This study suggests a role for routine OGD in patients with Lynch syndrome.

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Cite This Study

Tjandra et al. (2026) studied this question.

synapsesocial.com/papers/69edacdb4a46254e215b49a3https://doi.org/10.1097/mcg.0000000000002382
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