Evaluates PGF as a biomarker in HCC, suggesting its prognostic significance and underlying mechanisms.
PGF may serve as an independent prognostic biomarker in HCC. The developed pathomics model enables non-invasive PGF expression prediction through H&E image analysis. Mechanistically, PGF-associated molecular alterations involve inflammatory signalling, immune microenvironment remodelling, and frequent TP53 mutations, providing insights into HCC pathogenesis.
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Chen et al. (2026) studied this question.
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