Nasal Rosai–Dorfman disease: A case report and review of the literature

Rosai–Dorfman disease is a rare reactive histiocytic proliferation disorder. It is rarely reported in the literature, and its clinical manifestations vary depending on the location of occurrence. The clinical manifestations and imaging features are not characteristic, and the diagnosis mainly relies on pathology and immunohistochemistry. Here, we report a case involving the nasal cavity and paranasal sinuses, which did not exhibit typical symptoms such as painless cervical lymphadenopathy and fever. It could easily have been misdiagnosed as a malignant tumor before surgery. This case did however exhibit typical histopathological features. The patient was treated with surgery combined with hormone therapy and a good clinical outcome was achieved.