Why the study?
Does combination chemotherapy aggravate oxidative stress and cardiotoxicity in breast carcinoma?
Does combination chemotherapy aggravate oxidative stress and cardiotoxicity in breast carcinoma?
Combination chemotherapy in breast cancer aggravates oxidative stress, leading to cardiotoxicity.
May warrant closer cardiac monitoring in breast cancer chemotherapy; leaves open whether targeting oxidative stress alters outcomes.
The results from the present study show that oxidative stress is implicated in breast carcinoma and chemotherapy aggravates this oxidative stress which causes damage to many cellular targets and has the main side effect of cardiotoxicity.
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Amin et al. (2012) studied this question.
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