Is nocturnal hypertension or nondipping better associated with a worse cardiovascular risk profile?
The combination of nocturnal hypertension and nondipping identifies patients with the most severe cardiovascular risk profile.
Nondipping is related to more advanced disease (reduced renal function and clinical evidence of cardiovascular disease), whereas nocturnal hypertension is associated with albuminuria. The worst cardiovascular risk profile is present in patients exhibiting both nocturnal hypertension and nondipping.
Sierra et al. (Mon,) studied this question.