Early increase in red cell distribution width-to-platelet ratio is associated with poor prognosis in sepsis patients: a retrospective cohort study

During the early stage of ICU admission (0-6 days), RPR may serve as a dynamic biomarker reflecting evolving pathophysiological changes. Early increases in RPR were observed to be associated with a higher risk of in-hospital mortality. These findings suggest that longitudinal RPR trajectories may provide supplementary information regarding risk stratification and warrant further investigation in conjunction with established clinical assessments.