Why the study?
Is aerobic fitness or physical activity associated with skin microvascular reactivity in children and adolescents with type 1 diabetes?
Is aerobic fitness or physical activity associated with skin microvascular reactivity in children and adolescents with type 1 diabetes?
Higher aerobic fitness (VO2peak) is associated with better microvascular endothelial function in youth with type 1 diabetes, suggesting fitness may mediate vascular health in this population.
May support fitness assessment in youth with T1D; hypothesis-generating for causality and needs prospective confirmation.
No studies to date have evaluated the relationship between exercise and microvascular function in youth with type 1 diabetes mellitus (T1DM). Twenty-nine complication free children and adolescents with T1DM were assessed for skin microvascular reactivity, aerobic fitness (VO2peak) and physical activity. VO2peak but not physical activity was significantly and independently associated with maximal hyperemia of the skin microcirculation (p < .01). No significant associations were found between venoarteriolar reflex (VAR) vasoconstriction and VO2peak or physical activity. Aerobic fitness may be an important indicator or mediator of effective microvascular endothelial function in youth with T1DM.
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Roche et al. (2008) studied this question.