March 1, 1992European Heart Journal
Transient ischaemia refractory to conventional medical treatment in unstable angina: angiographic correlates and prognostic implications
Why the study?
Does complex coronary morphology correlate with greater and more refractory transient myocardial ischaemia in patients with unstable angina?
Population
86 patients admitted to the Coronary Care Unit for unstable angina
Comparison
Complex coronary morphology on angiography vs Regular and smooth morphology of coronary…
Design
Cohort
Follow-up
1 year
Authors
Discussion
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Member takes
Implication
Complex morphology signals more refractory ischaemia after medical therapy; leaves open whether morphology should guide revascularization decisions.
Structured PICO
Does complex coronary morphology correlate with greater and more refractory transient myocardial ischaemia in patients with unstable angina?
P
Population
86 patients admitted to the Coronary Care Unit for unstable angina
I
Intervention
Complex coronary morphology (CM) on angiography (eccentric stenosis with irregular borders, overhanging edges, or intracoronary thrombus)
C
Comparator
Regular and smooth morphology of coronary stenosis (RM) or coronary spasm (CS)
O
Outcome
Transient myocardial ischaemia (TMI) duration at admission and presence of residual ischaemia after 3 days of intensive triple drug treatmentsurrogate
In patients with unstable angina, complex coronary stenosis morphology is associated with greater transient myocardial ischaemia that is more often refractory to intensive medical treatment.
Cite This Study
Pozzati et al. (1992) studied this question.