Why the study?
Does pretreatment with antioxidant vitamins C and E prevent the transient reduction in endothelial function following a single high-fat meal in healthy, normocholesterolemic subjects?
Does pretreatment with antioxidant vitamins C and E prevent the transient reduction in endothelial function following a single high-fat meal in healthy, normocholesterolemic subjects?
Antioxidant vitamins C and E can prevent the transient endothelial dysfunction induced by a high-fat meal, suggesting an oxidative mechanism.
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No clinical recommendation for antioxidant pretreatment before meals; leaves open effects on cardiovascular outcomes.
Gary D. Plotnick (1997) studied this question.
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