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July 22, 1993New England Journal of Medicine700 citationsOpen Access

A Comparison of Directional Atherectomy with Coronary Angioplasty in Patients with Coronary Artery Disease

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ETEric J. TopolFLFerdinand LeyaCPCass A. Pinkerton

Key Points

  • The aim is to compare directional atherectomy with coronary angioplasty in patients with coronary artery disease.
  • Patients underwent either directional atherectomy or coronary angioplasty.
  • Follow-up was conducted for six months after the procedures.
  • Directional atherectomy led to a larger luminal diameter.
  • A small reduction in angiographic restenosis was observed, mainly in the proximal left anterior descending artery.
  • Athrectomy resulted in higher early complication rates and increased costs without clear clinical benefits.

Abstract

Removing coronary artery plaque with atherectomy led to a larger luminal diameter and a small reduction in angiographic restenosis, the latter being confined largely to the proximal left anterior descending coronary artery. However, atherectomy led to a higher rate of early complications, increased cost, and no apparent clinical benefit after six months of follow-up.

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Cite This Study

Topol et al. (1993) studied this question.

synapsesocial.com/papers/69eee09f0fb71af24d311c59https://doi.org/10.1056/nejm199307223290401
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