Population-based study shows longer epilepsy and drug-resistant epilepsy durations worsen seizure outcomes in children, suggesting early surgical referrals are crucial.
In this unselected population-based, pediatric, resective epilepsy surgery cohort, longer epilepsy duration is associated with worse seizure outcomes. Similarly, a prolonged duration of DRE was correlated with worse seizure outcomes. The findings emphasize the importance of early surgical referrals. Future multicenter studies are warranted to further clarify the relative prognostic value of DRE duration versus total epilepsy duration and to guide evidence-based criteria for surgical timing in children with epilepsy.
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Zheng et al. (2026) studied this question.
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