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April 27, 2026Biotechnology Letters0 citationsOpen Access

Development and validation of a novel latex particle-enhanced turbidimetric immunoassay for fecal calprotectin

ZZZhe ZhouSouthern Medical UniversityYLYu LiAnhui Jianzhu UniversityFZFeihu ZhangGuangdong Medical College

Key Points

  • To develop and validate a latex particle-enhanced turbidimetric immunoassay for fecal calprotectin (FCP) quantification.
  • Developed a novel immunoassay using latex particles and antibodies.
  • Compared with established ELISA for validation.
  • Focused on automation and suitability for high-throughput laboratories.
  • Achieved strong correlation with ELISA for FCP quantification.
  • Demonstrated rapid processing and automation advantages.
  • Supported translational potential in clinical settings.

Abstract

The PETIA showed strong correlation with the established ELISA for FCP quantification, offering a rapid, automated alternative suitable for high-throughput laboratories. This study, encompassing development from antibody to reagent, supports its translational potential.

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Cite This Study

Zhou et al. (2026) studied this question.

synapsesocial.com/papers/69eefc6dfede9185760d3858https://doi.org/10.1007/s10529-026-03733-5
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Clinical performance of a particle enhanced turbidimetric immunoassay (PETIA) for detecting fecal calprotectin2024
  2. 2The novel latex agglutination turbidimetric immunoassay system for simultaneous measurements of calprotectin and hemoglobin in feces2018 · 14 citations
  3. 3Assessing Intestinal Inflammation: A Comparison of Immunochromatographic Tests and ELISA for Fecal Calprotectin Detection2026
  4. 4Evaluation of a Particle Enhanced Turbidimetric Immunoassay (PETIA) for detecting calprotectin in sputum samples2026
  5. 5P0485Comparison of Fecal Calprotectin Levels Measured by Fluoroenzyme Immunoassay, Latex Agglutination, and Chemiluminescent Immunoassay Techniques in Inflammatory Bowel Disease2026