Decoupled Inflammatory Trajectories in Maternal Obesity: Reframing Peripartum Immune Resolution Beyond Redox Stability

Key Points

• This research examines how maternal obesity influences inflammation and immune responses during the peripartum period.
• Qualitative analysis of existing literature on maternal obesity and immune responses.
• Focus on inflammatory trajectories and immune resolution processes during pregnancy and childbirth.
• Identified distinct pathways of inflammation in obese maternity that differ from those in non-obese subjects.
• Proposed new frameworks for understanding immune responses beyond traditional redox stability.