Key result
Same-day discharge following elective M-TEER currently lacks sufficient data regarding feasibility and safety.
Why the study?
Data on the feasibility and safety of same-day discharge following mitral transcatheter edge-to-edge repair remain limited.
Does same-day discharge increase unplanned all-cause readmissions within 90 days compared to next-day discharge in patients undergoing elective M-TEER?
Cohort (n=39,804)
Yes
Does same-day discharge increase unplanned all-cause readmissions within 90 days compared to next-day discharge in patients undergoing elective M-TEER?
Answers are grounded in this paper and cite their sources.
Captured external expert commentary on this paper, strongest first. Original sources are linked where available.
“As operators increasingly adopt SDD – particularly at high-volume, resource-optimized centers – its broader implementation in the M-TEER population warrants thoughtful evaluation. Developing standardized criteria for SDD eligibility – potentially incorporating frailty scores, access site characte...”
Same-day discharge following elective M-TEER is associated with similar 90-day readmission risks and lower hospitalization costs compared to next-day discharge, suggesting it is a feasible and safe strategy for selected patients.
BACKGROUND: Data on the feasibility and safety of same-day discharge (SDD) following mitral transcatheter edge-to-edge repair (M-TEER) remain limited. OBJECTIVES: The objective of the study was to evaluate the contemporary trends and outcomes of SDD following M-TEER. METHODS: We reviewed the Nationwide Readmissions Database (2016-2022) to compare SDD following elective M-TEER with next-day discharge (NDD). The primary outcome was unplanned all-cause readmissions within 90 days. Secondary outcomes included 90-day heart failure (HF) readmissions and index hospitalization costs. Readmissions were compared using a Cox proportional hazards regression model. RESULTS: A total of 39,804 weighted hospitalizations for M-TEER were included, of which 1.2% involved SDD, 69.0% NDD, and 29.8% second- or third-day discharge (ScD/TDD). From 2016 to 2022, the proportion of SDD and NDD increased from 0.4% to 2.4% and 47.9% to 76.7%, respectively, whereas ScD/TDD decreased from 51.7% to 20.9% (all ptrend<0.001). SDD was associated with a similar risk of 90-day all-cause readmission (14.8% vs 12.5%; adjusted HR: 1.25; 95% CI: 0.90-1.74) and HF readmission (4.4% vs 3.7%; adjusted HR: 1.22; 95% CI: 0.67-2.22) and significantly lower index hospitalization costs ($38,029 vs $43,319; P = 0.03) compared to NDD. ScD/TDD was associated with a higher risk of 90-day HF readmission-but not all-cause readmission-and higher index hospitalization costs ($49,648 vs $43,319; P < 0.001) compared to NDD. CONCLUSIONS: SDD following M-TEER is uncommon but associated with a similar risk of 90-day readmission and lower index hospitalization costs compared to NDD. Further research is warranted to identify optimal patient selection criteria for SDD after M-TEER.
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Ismayl et al. (2026) conducted a cohort in Elective mitral transcatheter edge-to-edge repair (M-TEER) (n=39,804). Same-day discharge (SDD) vs. Next-day discharge (NDD) was evaluated on Unplanned all-cause readmissions within 90 days (HR 1.25, 95% CI 0.90-1.74). Same-day discharge following elective M-TEER was associated with a similar risk of 90-day all-cause readmission compared to next-day discharge (14.8% vs 12.5%; HR 1.25; 95% CI 0.90-1.74).
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