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April 27, 2026Cureus0 citationsOpen Access

Rheumatoid Arthritis-Associated Interstitial Lung Disease Presenting With Raynaud's Phenomenon: A Case Report

PGPrashant GhuleASAnil SontakkeSASaood Ali

Key Points

  • This case report aims to illustrate the occurrence of interstitial lung disease as an early manifestation of rheumatoid arthritis.
  • Detailed examination of a patient with respiratory symptoms and Raynaud's phenomenon.
  • Conducted high-resolution computed tomography (HRCT) to assess lung abnormalities.
  • Autoimmune evaluation included testing for rheumatoid factor and antinuclear antibody.
  • Patient exhibited bilateral inspiratory crepitations and positive rheumatoid factor.
  • HRCT revealed microcystic honeycombing, basal subpleural fibrosis, and traction bronchiectasis consistent with usual interstitial pneumonia (UIP).
  • Identified interstitial lung disease as potentially preceding rheumatoid arthritis-related joint symptoms.

Abstract

Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is a recognized extra-articular manifestation of rheumatoid arthritis. Pulmonary involvement may occasionally precede overt articular disease, creating diagnostic challenges. A patient presented with breathlessness for 2-3 months and joint pain of similar duration, along with bluish discoloration of the left middle finger, suggestive of Raynaud’s phenomenon. Respiratory examination revealed bilateral inspiratory crepitations in the infrascapular and infra-axillary areas. Rheumatoid factor was positive, while antinuclear antibody was negative. High-resolution computed tomography (HRCT) of the thorax demonstrated microcystic honeycombing, basal subpleural fibrosis, and traction bronchiectasis, consistent with a usual interstitial pneumonia (UIP) pattern. This case highlights ILD as a potential early manifestation of rheumatoid arthritis and emphasizes the importance of autoimmune evaluation in patients presenting with fibrotic ILD and systemic features such as Raynaud’s phenomenon.

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Cite This Study

Ghule et al. (2026) studied this question.

synapsesocial.com/papers/69eefdb5fede9185760d475fhttps://doi.org/10.7759/cureus.107697
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