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Lymphopenia increases vulnerability to infections in immunosuppressed patients, suggesting the need for careful management.
Lymphocytopenia or lymphopenia is diagnosed when the absolute lymphocyte count decreases below 1000 mL/L. This is a serious condition that makes the patient vulnerable to a myriad of opportunistic infections, which can be life-threatening. This laboratory-diagnosed condition is seen in patients who receive chronic immunosuppressive medications after organ transplant, in patients infected with human immunodeficiency virus and other autoimmune diseases, etc. Safeguarding from opportunistic infections and treating the underlying pathology, along with allograft surveillance, are ways of managing these patients.
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Jolly et al. (2026) studied this question.
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