Does chronic vagus nerve stimulation improve autonomic control and attenuate heart failure progression in a canine high-rate pacing model?
Chronic vagus nerve stimulation attenuates heart failure progression and systemic inflammation in a canine model, highlighting its potential as a novel HF therapy.
Chronic VNS improves cardiac autonomic control and significantly attenuates HF development in the canine high-rate ventricular pacing model. The therapeutic benefit of VNS is associated with pronounced anti-inflammatory effects. VNS is a novel and potentially useful therapy for treating HF.
Zhang et al. (Wed,) studied this question.