July 28, 2011PLoS ONE173 citationsOpen Access
Adipocyte Hypertrophy, Fatty Liver and Metabolic Risk Factors in South Asians: The Molecular Study of Health and Risk in Ethnic Groups (mol-SHARE)
Structured PICO
Does adipocyte area account for ethnic differences in metabolic risk factors between South Asians and white Caucasians?
P
Population
South Asians and white Caucasians
O
Outcome
Adipocyte area, insulin, HDL cholesterol, adiponectin, and ectopic fat deposition in the liversurrogate
Increased adipocyte area in South Asians accounts for ethnic differences in metabolic risk factors and liver fat deposition compared to white Caucasians.
Abstract
South Asians have an increased adipocyte area compared to white Caucasians. This difference accounts for the ethnic differences in insulin, HDL cholesterol, adiponectin, and ectopic fat deposition in the liver.