Why the study?
Does GR32191B inhibit TXA2-mediated vasoconstriction in human radial artery grafts?
Does GR32191B inhibit TXA2-mediated vasoconstriction in human radial artery grafts?
GR32191B may be useful in reducing complications related to vasospasm in human radial artery grafts.
May reduce radial graft vasospasm complications; hypothesis-generating from Level 5 animal data and requires human trials.
GR32191B is a highly potent and specific TP receptor antagonist for the human RA. It may be particularly useful in inhibiting TXA2-mediated vasoconstriction and therefore in reducing the complications related to vasospasm in this graft.
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He et al. (1999) studied this question.
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