February 7, 2006Circulation
Prediction of Lifetime Risk for Cardiovascular Disease by Risk Factor Burden at 50 Years of Age
Why the study?
Does the absence of established risk factors at 50 years of age predict lower lifetime risk for cardiovascular disease and longer survival?
Population
Individuals at 50 years of age
Comparison
Absence of established cardiovascular risk factors vs Intermediate or high risk factor burden
Design
Cohort
Authors
Discussion
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Member takes
Implication
Supports midlife prevention emphasis; hypothesis-generating for causal effects on lifetime CVD risk.
Structured PICO
Does the absence of established risk factors at 50 years of age predict lower lifetime risk for cardiovascular disease and longer survival?
P
Population
Individuals at 50 years of age
I
Intervention
Absence of established cardiovascular risk factors
C
Comparator
Intermediate or high risk factor burden
O
Outcome
Lifetime risk for cardiovascular disease and survivalhard clinical
The absence of cardiovascular risk factors at age 50 predicts very low lifetime CVD risk and longer survival, emphasizing the critical importance of early preventive efforts.
Cite This Study
Lloyd‐Jones et al. (2006) studied this question.