Why the study?
Are early neutrophil and monocyte counts associated with myocardial reperfusion and contractile recovery in patients with acute MI treated with primary PCI?
Are early neutrophil and monocyte counts associated with myocardial reperfusion and contractile recovery in patients with acute MI treated with primary PCI?
Monocyte counts in the early days post-MI are independently associated with contractile recovery at 6 months in patients treated with primary PCI.
May inform post-MI risk stratification after primary PCI; leaves open causal role of monocytes in contractile recovery.
The present study shows that neutrophils and monocytes counts on the first days after acute MI treated with primary PCI are related to markers of effective myocardial reperfusion such as MBG 2-3 and ST-segment resolution. However, only monocytes and MBG are significantly and independently associated with contractile recovery of the infarcted area at 6 months.
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Mariani et al. (2006) studied this question.