Why the study?
Is in-hospital non-ICH bleeding independently associated with increased mortality at 30 days or 1 year in STEMI patients receiving fibrinolytic therapy?
Is in-hospital non-ICH bleeding independently associated with increased mortality at 30 days or 1 year in STEMI patients receiving fibrinolytic therapy?
In STEMI patients treated with fibrinolytic therapy, non-ICH bleeding is not independently associated with increased short- or long-term mortality, unlike cardiogenic shock, age, and ICH.
Non-ICH bleeding may not independently drive mortality in fibrinolytic-treated STEMI; leaves open whether avoidance strategies improve survival.
Cardiogenic shock, age, and ICH were important independent correlates of 30-day and 1-year mortality in STEMI patients receiving fibrinolytic therapy. In-hospital non-ICH major and minor bleeding were not independently associated with increased mortality at 30 days or 1 year.
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Giugliano et al. (2010) studied this question.
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