Does Renal Sympathetic Denervation improve hemodynamic alterations and LV stiffness in patients with HFpEF?
Renal sympathetic denervation may partly normalize hemodynamic alterations and LV stiffness in patients with HFpEF, suggesting a potential therapeutic role.
Patients with HFpEF undergoing RDN showed increased stroke volume index, vascular, and LV stiffness as compared to no-HF patients. Following RDN those hemodynamic alterations and reduced systolic and diastolic LV stiffness were partly normalized, implying RDN might be a potential therapeutic strategy for arterial hypertension and HFpEF.
Kresoja et al. (2021) studied this question.