Why the study?
Is mitral annular disjunction specifically associated with prolapse of the mitral valve leaflets?
Population
13 hearts (7 normal hearts and 6 with prolapse owing to floppy mitral valves)
Comparison
Histological examination of the mitral… vs Normal hearts
Authors
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Mitral annular disjunction represents normal anatomy rather than prolapse-specific pathology; challenges prior assumptions and leaves open its clinical relevance.
Is mitral annular disjunction specifically associated with prolapse of the mitral valve leaflets?
Mitral annular disjunction is an anatomical variation of the normal morphological characteristics of the left atrioventricular junction, rather than a specific pathological feature of mitral valve prolapse.
Angelini et al. (1988) studied this question.
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