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September 7, 2021Acta cardiologica. Supplementum24 citations

Ticagrelor improves systemic immune-inflammation index in acute coronary syndrome patients

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MAMehmet Koray AdalıİBİpek BüberOKOğuz Kılıç

Structured PICO

Does ticagrelor improve inflammatory parameters (NLR, MHR, PLR, and SII) in PCI-treated ACS patients compared to clopidogrel?

P
Population
Acute coronary syndrome (ACS) patients treated with percutaneous coronary intervention (PCI)
I
Intervention
Ticagrelor
C
Comparator
Clopidogrel
O
Outcome
Inflammatory parameters including neutrophil-to-lymphocyte ratio (NLR), monocyte-to-high-density lipoprotein ratio (MHR), platelet-to-lymphocyte ratio (PLR), and systemic immune-inflammation index (SII)surrogate

Ticagrelor may offer additional anti-inflammatory benefits over clopidogrel in patients with acute coronary syndrome undergoing PCI.

Abstract

NLR, MHR, PLR, and SII levels were lower in ACS patients treating with ticagrelor. Ticagrelor may improve these inflammatory parameters in percutaneous coronary intervention (PCI)-treated ACS patients compared to clopidogrel.

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Cite This Study

Adalı et al. (2021) studied this question.

synapsesocial.com/papers/69effa6fbce9831ba4f73b6fhttps://doi.org/10.1080/00015385.2021.1973770
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Also Consider

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  1. 1Anti-Inflammatory Strategies for Ventricular Remodeling Following ST-Segment Elevation Acute Myocardial Infarction2014 · 296 citations
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  4. 4Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study2013 · 163 citations
  5. 5Prognostic Value of Neutrophil to Lymphocyte Ratio in Patients Presenting With ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention2012 · 201 citations