Reversal of Severe Heart Failure With a Continuous-Flow Left Ventricular Assist Device and Pharmacological Therapy
Why the study?
Does a continuous-flow left ventricular assist device combined with pharmacological therapy improve reversal of severe heart failure in patients with end-stage heart failure secondary to nonischemic cardiomyopathy?
Population
Patients with end-stage heart failure secondary to nonischemic cardiomyopathy
Design
Other
Authors
Discussion
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Member takes
Implication
May support LVAD plus pharmacology for recovery in nonischemic cardiomyopathy; hypothesis-generating and requires randomized confirmation before practice change.
Structured PICO
Does a continuous-flow left ventricular assist device combined with pharmacological therapy improve reversal of severe heart failure in patients with end-stage heart failure secondary to nonischemic cardiomyopathy?
P
Population
Patients with end-stage heart failure secondary to nonischemic cardiomyopathy
I
Intervention
Continuous-flow left ventricular assist device (nonpulsatile flow) combined with pharmacological therapy
O
Outcome
Reversal of severe heart failure
A combination of a continuous-flow LVAD and pharmacological therapy can achieve reversal of end-stage heart failure in patients with nonischemic cardiomyopathy.
Cite This Study
Birks et al. (2011) studied this question.