Why the study?
Does the presence of orthostatic hypotension predict all-cause mortality and coronary events in middle-aged individuals?
Population
Middle-aged individuals (The Malmo Preventive Project)
Comparison
Presence of orthostatic hypotension (OH) vs Absence of orthostatic hypotension
Design
Cohort
Authors
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May support OH screening for risk stratification in middle-aged adults; extends observational data but leaves causal effects and interventions open.
Does the presence of orthostatic hypotension predict all-cause mortality and coronary events in middle-aged individuals?
Orthostatic hypotension, particularly an impaired diastolic response, is an independent predictor of all-cause mortality and coronary events in middle-aged individuals.
Fedorowski et al. (2009) studied this question.
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