April 25, 2000Circulation358 citations
Severe Aortic Stenosis With Low Transvalvular Gradient and Severe Left Ventricular Dysfunction
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Structured PICO
Does aortic valve replacement improve functional status and survival in patients with severe aortic stenosis, low transvalvular gradient, and severe left ventricular dysfunction?
P
Population
Patients with severe aortic stenosis, low transvalvular mean gradient, and severe left ventricular dysfunction
I
Intervention
Aortic valve replacement
O
Outcome
Functional status and postoperative survivalhard clinical
Aortic valve replacement is associated with improved functional status in patients with severe aortic stenosis, low gradient, and severe LV dysfunction, despite increased operative mortality.
Abstract
Despite severe left ventricular dysfunction, low transvalvular mean gradient, and increased operative mortality, aortic valve replacement was associated with improved functional status. Postoperative survival was related to younger patient age and larger aortic prosthesis size, and medium-term survival was related to improved postoperative functional class.
Cite This Study
Connolly et al. (2000) studied this question.