⌘+K

Pulse Explore Communities Researchers Journals

Home Communities Explore

April 1, 2026IBRO Neuroscience ReportsOpen Access

Mind-Body Exercise as Epigenetic Modulators: Rewiring Neural Circuits for Stress Resilience and Cognitive Aging

Mengbi Gu Jiliang Kang Yi Zhou Lin Lin Chunyan Li Mengzi Wu Qiaochu Fan Min Tang

View Full Paper

Ask AI

Bookmark

Share

Key Points

The aim is to evaluate the link between mind-body exercises and their epigenetic effects, particularly on cognitive function and stress resilience.
Critical evaluation of empirical studies linking MBEs to epigenetic changes.
Focus on biomarkers related to stress regulation and neuroplasticity.
Proposal of a conceptual epigenetic-neural circuit model for future research.
Current evidence supports a connection between MBEs and epigenetic changes, yet findings are mostly preliminary.
Most studies reviewed are cross-sectional, with small sample sizes and limited mechanistic validation.
Identification of key biomarkers such as BDNF and NR3C1 is highlighted as critical for understanding stress resilience.

No abstract yet

We only have this paper's title and publication details.

Read it at the source→

Implication

This review explores how mind-body exercises affect epigenetic mechanisms in relation to cognitive aging and stress resilience.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Gu et al. (2026) studied this question.

synapsesocial.com/papers/69f04e08727298f751e7213b https://doi.org/10.1016/j.ibneur.2026.04.010

View Full Paper

Ask AI

Bookmark

Share

Keep reading

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1A Meta-Analysis of Studies of the Effect of Mind Body Exercise on Various Domains of Cognitive Function in Older People With or Without Mild Cognitive Impairment2025 · 4 citations
2Epigenetic and Neurogenomic Mechanisms Linking Physical Activity to Brain Plasticity and Cognitive FunctionNarrative Review · 2026 · 2 citations
3The neurobiological effects of mind–body exercise: a systematic review and meta-analysis of neuroimaging studiesmeta-analysis · 2023 · 41 citations
4Exercise-Induced Epigenetic Modifications: Implications for Healthy Aging2025
5The effect of mind–body exercise on cognitive function and neuroplasticity in elderly people with mild cognitive impairment: a systematic review and meta-analysis2025 · 3 citations

More related papers

Mapping Evidence on the Effectiveness of Mind-Body Interventions and Brain Gym on Cognitive Function in Older Adults: A Scoping Review2026
Transcriptional Signature of Mind-Body Interventions on Inflammatory Gene Expression: A Systematic Review and Meta-Analysis2026
Long-Term Physical Exercise and Mindfulness Practice in an Aging Population2020

More from IBRO Neuroscience Reports

Histopathology-correlated evaluation of magnetic resonance spectroscopy for high-grade glioma prediction: A small-scale neuro-oncology study with exploratory machine learningWed,
Research landscape of neurodegenerative diseases and brain energy metabolism: A multi-database integrative analysisSat,