Effect of Transcranial Magnetic Stimulation in Patients with Postherpetic Neuralgia and Comorbid Depression: A Randomized Controlled Trial

April 25, 2026Pain and TherapyOpen Access

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Key Points

This research aimed to evaluate the effectiveness of transcranial magnetic stimulation in alleviating pain and depressive symptoms in patients with postherpetic neuralgia.
Conducted a randomized controlled trial (ChiCTR2500096978).
Included patients with postherpetic neuralgia and comorbid depression.
Evaluated the impact of transcranial magnetic stimulation on pain and depression.
Transcranial magnetic stimulation significantly reduced pain intensity and depressive symptoms.
Results indicate a positive effect on the quality of life for participants undergoing treatment.

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Randomized trial shows pain relief in postherpetic neuralgia patients with depression, suggesting effective treatment options.

Chinese Clinical Trial Register Identifier: ChiCTR2500096978.

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Xu et al. (2026) studied this question.

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