June 4, 2003Circulation
B-Type Natriuretic Peptides and Ejection Fraction for Prognosis After Myocardial Infarction
Why the study?
Do concurrent measurements of B-type natriuretic peptides and LVEF improve prognostic risk stratification for death, heart failure, and new myocardial infarction in patients with acute myocardial infarction?
Population
666 patients with acute myocardial infarction
Design
Cohort
Follow-up
3 years
Authors
Discussion
Loading...
Member takes
Implication
May refine post-MI risk stratification via combined LVEF and N-BNP; hypothesis-generating for prospective trials.
Structured PICO
Do concurrent measurements of B-type natriuretic peptides and LVEF improve prognostic risk stratification for death, heart failure, and new myocardial infarction in patients with acute myocardial infarction?
P
Population
666 patients with acute myocardial infarction
I
Intervention
Concurrent measurements of BNP, amino-terminal BNP (N-BNP), norepinephrine, and radionuclide LVEF
O
Outcome
Death, heart failure, and new myocardial infarctionhard clinical
Combined measurement of N-BNP (or BNP) and LVEF provides substantially better risk stratification for major adverse events after myocardial infarction than either marker alone.
Cite This Study
Richards et al. (2003) studied this question.