Why the study?
Does a mechanical heart valve improve survival or reduce valve-related complications compared to a bioprosthetic valve in men undergoing aortic or mitral valve replacement?
Does a mechanical heart valve improve survival or reduce valve-related complications compared to a bioprosthetic valve in men undergoing aortic or mitral valve replacement?
At 11 years, mechanical and bioprosthetic valves provide similar survival and overall complication rates in men, but with differing profiles of structural failure and bleeding.
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Supports individualized valve choice by bleeding risk and durability needs in men; confirms long-term equivalence beyond prior shorter trials.
Hammermeister et al. (1993) studied this question.
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