What question did this study set out to answer?

Resolve controversies regarding the underlying arterial pathology that drives acute myocardial infarction, crescendo angina, and sudden ischaemic death.

April 1, 1985HeartOpen Access

Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina.

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Authors

MDMichael J. DaviesSouth Australia Pathology ATAnthony ThomasDeakin University

Discussion

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Implication

Pathological review reveals coronary plaque fissuring and thrombosis in acute coronary syndromes, highlighting their central role across diverse ischaemic presentations.

Key Points

Resolve controversies regarding the underlying arterial pathology that drives acute myocardial infarction, crescendo angina, and sudden ischaemic death.
Examined pathological evidence regarding the presence and mechanisms of coronary artery thrombosis in acute coronary events.
Evaluated historical discrepancies among pathologists regarding the causal role of thrombi in acute ischaemia.
Identified atherosclerotic plaque fissuring as the primary trigger leading to acute coronary artery thrombosis.
Established coronary thrombosis as the common pathological mechanism driving acute myocardial infarction, sudden ischaemic death, and crescendo angina.

Cite This Study

Davies et al. (1985) studied this question.

synapsesocial.com/papers/69f14b572811130d0cde2124 https://doi.org/10.1136/hrt.53.4.363

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Implication

Pathological review reveals coronary plaque fissuring and thrombosis in acute coronary syndromes, highlighting their central role across diverse ischaemic presentations.

Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina.

Discussion

Member takes

Implication

Key Points

Cite This Study

Plaque fissuring--the cause of acute myocardial infarction, sudden ischaemic death, and crescendo angina.

Discussion

Member takes

Implication

Key Points

Cite This Study

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