Why the study?
Does myocardial T1 mapping detect diffuse myocardial fibrosis in patients with chronic aortic regurgitation compared to healthy volunteers?
Population
8 patients with chronic aortic regurgitation and normal coronary arteries awaiting surgical valve replacement
Comparison
Myocardial T1 mapping using a modified… vs 15 healthy volunteers with previously…
Design
Case-control
Authors
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T1 mapping may detect diffuse fibrosis in chronic AR; hypothesis-generating and requires prospective validation before clinical use.
Does myocardial T1 mapping detect diffuse myocardial fibrosis in patients with chronic aortic regurgitation compared to healthy volunteers?
Segment-based myocardial T1 mapping can detect differences in relaxation times in patients with chronic aortic regurgitation, suggesting the presence of diffuse myocardial fibrosis.
Sparrow et al. (2006) studied this question.
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