October 15, 1996Circulation
Mechanism of Spontaneous Termination of Functional Reentry in Isolated Canine Right Atrium
Why the study?
Does excitation of the core by an outside wave front lead to termination of functional reentry in isolated canine right atrium?
Structured PICO
Does excitation of the core by an outside wave front lead to termination of functional reentry in isolated canine right atrium?
P
Population
9 isolated canine right endocardial atrial tissues (3.8 by 3.2 cm wide)
I
Intervention
Premature point stimulus (S2) to induce reentry
O
Outcome
Mechanism of termination of functional reentry (excitation of the core or collision)surrogate
Functional reentry in the atrium can be terminated by direct excitation of the excitable but nonexcited core or by collision with an outside new wave front.
Authors
Discussion
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Implication
Core excitation by colliding wavefronts may terminate atrial reentry; hypothesis-generating in canine models and leaves open human translation.
Cite This Study
Ikeda et al. (1996) studied this question.